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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74e9cfe114c32f8c0cd5ad689311d8973c371f41f1c3f129b1953eb5bfc15032' 
  AND token = 's+M5nydQSX6fKX/52pALZ36vpOkDj65u6mZPKSHsbn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}