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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ced5dfa5431030ea9e769b685f1d4f2fe83b9220aa962a7a6b024a3eaa9b190' 
  AND token = 'H6LyVRtRzXsjVNkZX9zFd8gPGCg2hFiuashdQ7VqVKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}