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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e93d96d942ee3175706c5528abf69b5b62cfc69da825600bc9a4ac931be89e8' 
  AND token = '+dZ4Bnfqbk+PmunET/RBbM9Kk7Rf2So1ac28v7YVzC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}