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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5b88d71cff76aaa56553b982b6416785b96bf27683aa4c7e1c9caa78e5110f' 
  AND token = '27Y45YuKe+tsAh1sdy3OkccmlB9VGxK2P2S2+yKqicI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}