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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8804e0bd7b11cb3240839b1d2a5d7fe6013f91942f54770481213d7a897b3997' 
  AND token = 'IHCRCkxJIg/csm61M6w2qfaczCJE0qhOos6uitZ7m7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}