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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01164ed5bda7118c0a327c1f26dba2da79e059d5819abbae71fb6462177fcfa4' 
  AND token = 'ZX/5U1+1DvZlAzg//8+/76iHkF9YKLs+qq/l3Gc2EMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}