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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eacdee337855349436f67d214ad530cd58e87ad2b94c04f4e7af207abaeaf30' 
  AND token = 'zVNW3mw1/5CdXLng+aSLPNIhRPklP5C+a9Cv9cUo2s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}