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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b064ee93336dbf20ccd342297acea2db0ba0b0dc6f314ca44770920e322d61de' 
  AND token = 'ryx5QUrOeWD56t5YlEoTQWHK4JTgFmAcwKN4EXVWlQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}