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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50668b2fb2c94c87b3a10e77868d65e7433d2c32a35034a69367148972e0777f' 
  AND token = 'cOhJi28VnY3qmPWePMWdyx1SjzC4LNlPG8AcPlR+aHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}