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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf280236dd9d999b58e8522259b81380c2f6ef73c17e0de308f01c7930fe169c' 
  AND token = 'G+rVvOupQnPn+AS4dsyV14OXVTEH+9riOS9kDnVYOag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}