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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e800fd796da393672809c79afd28e2da8aa5e9d011371c67b42d6ae616c5b6b5' 
  AND token = 'EYOQ7I1Zd9PAHy4nqhhL90KBIPxgogoUPLaBI/zSWwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}