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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b33582ea2fca13ef2b39798d8791b827d5f66397845220915520614951e21b2e' 
  AND token = 'jQIGYNd35qTNRqH05yrs62oiil0N+IoWQEuCZ6x79lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}