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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73312d4aa9e95492d99878182d134d1e464e6daa09224e9e73d5a4e4ee566998' 
  AND token = 'gjDrJuwrxCnkRFFmyGgYjV0yNQr7khHsWDT0NNjXAVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}