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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6e29e7831391e7b38b278a4a4208362f5d7ca1ea4917241683157edffb598bd' 
  AND token = 'cnreQ5/BnM4hwZzTxZ7b8u5ezFl0nFy9//xotpzyyMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}