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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aa1132d0829d18e6ecc56920f96b796d4386b47b1ad68a0a073cc650157d646' 
  AND token = '3VG9aFEm9NbWB1TCotJfxnzfe8/+YvucCC1roCm6YS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}