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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a6af94219d364d2e2916e62a03c6d6acf012933197e778b7d6771b9996f910' 
  AND token = 'GQ+e7MZaaZf+Zy1doh5FY4iCUXYpNo2ws/hUFTMi6ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}