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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e0bf1dbaaa6cd27d0668905e685a63a8d998d54805b145cf29fc983977ab38c' 
  AND token = 'vyO1NucmwI2XOCyib2uh162WIPtrAFoNxKbOE3bbCa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}