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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406b8c3eab9b052a0f1205f20321fb4753eb40760be3eaddc0d0df1b53295a6e' 
  AND token = 'HBL66NcnkN0mYY/nkGFZb9oR+N1obhcIM+j+eMU3K58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}