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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '514fc43a2dbb2aded21532ea76bc9eec34a7d60759854475b5a93cdeafc7e7aa' 
  AND token = 'uVo+UwA3LQG9L1DI5c2+LSaQa7uimRGC4+75wczqcu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}