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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9762231ae09d3abf57c3e1b9181f75c415588fc2a939e20842e2e71d8b0a436' 
  AND token = 'XYvdGZr43e4pU2nVkF2pBmJhmnla3DWVjuAmH5ZOSVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}