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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec16126e5c499b7e3567ccb8d6bae40e87ee476d5df85f2fc5819a1121519c88' 
  AND token = '8fUeO1odHJXPDaQQoVVq9e30oW0TDaO3W2DT6J6WiuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}