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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaad529b59a687ee4e937b6966f6b1b6dd4b945fa7c7ee3da58a3ce28b494e46' 
  AND token = 'sN9NWI1g/zDVq35b0SyOupRR84fMbk+F+glMq/rxx6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}