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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1957f075defb23648ffd09817b0bf2d59c6d7559dbf0c95da2e00338b1fb935' 
  AND token = 'SvNo9BgHaKQt4qUoXJHee6OZ24mggwsyEQQ353szNjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}