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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b39d8e49c6d34aa1f4b9d7e999300cfae114147541311c39480723e0ffe0158' 
  AND token = 'ZX5FPh0a6gMDen6OWJSjljd1e+jsXkcm89XeXffYVu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}