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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ab15152067c009f7f0635307ebd2a7791af6c58764e42ecaaa30810217e4da' 
  AND token = 'ZFuAT+YmfYBiCIfPIq4UqjMN38/n0F2M1k1+CB5blz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}