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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb273dc9e80d871eba22d21b4a04da157df77b450e7754152ded378a5fc732ef' 
  AND token = 'escSBrpkyDRjMmPS7HOVbD9gXln8eEpatQQTgXSoLoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}