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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f65d54ed0495a0750e2b7d40fcd48e4080246e33d6c807db7a365aec0e1131f' 
  AND token = 'Ub1PrfMihuGFIuk2efUdaifA6Ah2QLYceyW4L8Ol0CY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}