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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4f3b6435f3269135d026b9e752508ece6be55ad49605c6891ebaba4e5b42a85' 
  AND token = 'gFMJ9Q6LaPWj+1L9W86YSGy+3e8vL2Ks5F8bpPrOZsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}