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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c7afaff917eb5258e4fa5b1f1ea95af679bc245b7e53dc2ee24421a3014b5e' 
  AND token = 'lxNhjN9dG2K1bDXs+iXwWMrO4b3DLQveJ/NZ4nr9gDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}