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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3722ae659f8dad47ed8ecca6c599eba6b9326556aa868e55cf0ea9d30a37a1c6' 
  AND token = 'iuEU/eg3OdXhxwTTpaGXIcw7SWcKIy6yA9bVgXci8Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}