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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39d562d2894da378d61d26738247151b64720e820aa528953f62525bec850d24' 
  AND token = 'u5ZyJwNoXkIoOy/XHwONQR3S1fN10/b5VE0Xk1mj2Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}