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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aea1e9c840589efc89971b9a25175b764141cce264d8efe3e99e5c5c683fc06' 
  AND token = 'mZTL2IyaeIy2N1buDGF0tzYIdbCeYTPqRnl4rjmcue8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}