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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3de39760317aa2da8ac20a2717e4089c90837aa6bb65d3abb40804d061c911' 
  AND token = 'Da2cMgJWYJUYKPnlNEhAtXLj4e6jsTDKs1i1kTxKK54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}