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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f193de570e7a171d9b039b1d2ab2b12a9aa7bd6d66673cf07740a54119857409' 
  AND token = 'Gug9HYbsYh7S3k/wkNugecTSzcD93AJlbaQz9r8qQyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}