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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '286895d10a2f6f1368321e37184dbe40bebc06ee1bb3f0b5ed8e8d1e16a43121' 
  AND token = '9qY5t6DgE+AtXXyHKTCFRxPWCFf6yBzxJJXxw23EdaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}