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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1a13cc6e2eff8bdda3668dd0937cbe8d1b604d91323fa8634cc508cf4f6226' 
  AND token = 'v0j6ePWdHp5ZllOC8Ev4JCoIz0Q7aihiY4YRwMKKZvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}