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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c5f43d853c085b466c6d41539877c7abb75fca18fbf334ff34b37f377c72c36' 
  AND token = '4/IPYXSUlaq9/48otzUMZacwidiVdhYLqng3cIxuusk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}