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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd8e01b18caa1ecbe7fc914f8c72aa7cab95826c1a3892de5c443b9a19d0189' 
  AND token = 'OyBo23XHOaQjRj7zln0TDuwqUPQhB+46LhI/RLM0ywQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}