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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '542435606b96cd934b0526aaa5681fed8414f9d56246199e69c41a400a26b1ff' 
  AND token = 'M2PxRFDwWy+nKaT+mSlYnA85zF8h1UM+O+hb1XNaiuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}