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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429eae28d7bb91a318b79a52660d1f9e2a302f721cc90e52c2fe37f20e53f09f' 
  AND token = '6k18Dxy4w+IKdCtlBKGSqotrztbvOKrRnFkIp9E1vSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}