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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446ee9137027d3b50b4ec3718e58c88e230145ee9bca1f81b01aecf110208aba' 
  AND token = 'vWIjBXuW2nE2yw0tk94JdLaDGoE58j8VxckcqlAm3UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}