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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fc42b1aa6e38921ac3bacf1b10193dc33e494063c96ab90cc92e4a51a827ab' 
  AND token = 'neSlVxD+gw1d57kohovYVosTazre1ZBL57lVKdGTY9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}