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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df0569da6e38e2f3360b746433d4861eaa1520f922fdf7d8effa5fc2c5f37ea' 
  AND token = 'cGyUJZZN3QoexCMmo6+obDlfRF58Wi5WZxHjjVHOepQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}