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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05a8325c8e469d3f1e397ec23dffc44f0e75e1c20063459a1c2d3d679ad2970' 
  AND token = 'TxOjQdW4PcJOI4NIvryq4aQhgdcYKW8VZyhpMTDDfOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}