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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ab1e89e1eae79a8121fe2bed8a60d94b4dbd23cbac79a322a7fdf7c4d65cb7' 
  AND token = 'tDw2qK6K2x2CHTMmPIqd8NlQTf2f2krN8ai5CJGh7Ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}