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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd3cc0947f851bf7365bd610e41b15f78be38072f26cb833c228ae5bff084e65' 
  AND token = 'Lk3RLUicD3P4z3K2xamStIE4mC+cC/8crrYxtt9hNpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}