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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21785413b1e0c0a29c7948a52f1b037a123a209e4b8d51ddbe78d0d38757d321' 
  AND token = 'agLyGDJ7Wq2+pb+H+uFJuCrjuuFACSfAdA0ITp3pgqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}