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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5871a7340aa549be767f59f3845905ad1165ace3eedfa8f1c4b6c626f6c19da2' 
  AND token = 'qMcfWkKQUdRsvxkq6agEMGIN5aQJRFjvKlRgZFEfXTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}