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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de464063a0d4b4a4ec700ce2c132425c75117549204ff59ad1ca54568617e09' 
  AND token = 'KD6Vx653T/FvFNiKtoeQoDd5VGkcLIdOSGUHjzCT+Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}