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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9c5b499afdd67ecd0cab17e55ffa7e3b4daa8ed63df91c9a02f4543a0e8429d' 
  AND token = 'Ne8/xLN5RqeWeybOBaqOT0KSyipfZQI0ESvPuAV9AHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}